Be sure to take a little walk after a few drinks. It's easy to be feeling good while sitting down and drinking, and then feel way to drunk once you stand up and move around.
Pace your drinks and don't have to many too quickly. I like to keep to two or three drinks an hour if I wana cut loose and have fun without feeling like death later. This will vary from person to person so maybe keep it to two drinks since your not used to being drunk drunk.
Have lots of water.
Getting high after getting drunk is a fast way to get the spins. Don't do this. It's not fun.
Eat before you drink.