It worked pretty well for me in the twenty to thirty mile per week range, but as others have mentioned I also suffered a constant stress in my Achilles
Do you trail run at all, or mostly road run? I know a few people who love altra zero drops for trails, but can't handle the zero drop feeling for road shoes.
I think trails are more forgiving since you are slower, and since the uphills/downhills are more intense on trails, it's nice to have a flat shoe.
Btw, the altra vanish are their racing/tempo shoe, and they are labeled "zero drop", but runrepeat.com measured the vanish carbon 1 and 2, and found they actually had a drop of 5.4 and 3.7 mm, respectively. I can't say if the non-carbon version actually has a drop as well, but I have a pair and it feels like they do. They are a slimmer fit than other altras, but it is nice to have something with a more responsive foam for speedwork.