I use a 3090 with ZorinOS and it has some drawbacks (for some reason would not dim the screen when inactive until recently, tearing in most games, sometimes have to tweak nvidia drivers for games to work), but as far as i know, not many for 3d rendering itself (i haven't rendered big scenes though, but i've worked quite some time testing shaders, modeling or tracking and no issue for now).

Maybe nvidia bad reputation with linux applies mostly to gaming, but i'm not that sure.