We generally refer to the Founding Documents - the Declaration of Independence, the Constitution, and the Bill of Rights, with equal weight. They are the three founding Documents on display in DC.
The Declaration of Independence is the statement that made us a Nation, and is every bit as important and relevant as the Constitution. In fact, until the Constitution was ratified in 1789, this was the sole document that defined America in the 13 years between.
So the opening line, declaring all men to be created equal, is huge. Further, it refers to these things as God-given rights, which means they cannot be taken away by any human, including a president, or even a long.
And "Men" is a metaphor. You say it excludes women, but in fact, it doesn't even really include men. It means people in general, ALL people.
Further, it doesn't even include the racial element that contemporary society likes to ascribe to hypocrisy. When they were talking about All Men Being Created Equal, they didn't mean racially, or even economically. They meant equal as far as class distinctions. Specifically, they were rejecting as a society, the notion of an Aristocracy, in which some people are literally considered to be better quality humans in every way, simply because of their family influence. That superiority gives them great advantages in education, business, government, courts, military, etc.
Not only were they rejecting the Aristocracy, they were literally founding a new nation with that as one of its founding elements. At that time, a totally new nation hadn't been created in human memory, and now that this enormous uncharted landmass had been discovered, here was the first actual nation, that wasn't just a colony of predatory European nations. ALL of those nations recognized the concept of Aristocracy, and none of them liked the idea of a NEW nation where the Aristocracy wasn't respected.
Of course, France broke with the rest, and supported the Continental Army, but that was more a matter of sticking it to England. The Enemy of My Enemy is My Friend, and all that. Considering that our revolution inspired their revolution a few years later, with a much nastier outcome, perhaps it wasn't the French Monarchy's best poke at the British. Worked out good for us, though.