The difference is that economics is a social science, masquerading as a hard science. Nothing wrong with the social sciences but they often present themselves as though the results they've found are akin to a hard science experiment with the lowest R values on record. In fact, ironically, most economists tend to look down their noses at the other social sciences and I think it's causing them a lot of dukkha.
Ironically, it's the social sciences that would help them realise that their discipline was already enough, as it was, all along.
The real problem came when neoclassical economics was rebranded as "just basic economics!" and not one of many conflicting, equally supported, schools of thought.