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Scientists reverse Alzheimer’s in mice with groundbreaking nanotech (www.sciencedaily.com)
submitted 11 months ago by to c/neuro@lemmy.world
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[–] 28 points 11 months ago (3 children)

"Only 1h after the injection we observed a reduction of 50-60% in Aβ amount inside the brain"

Wow.

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  • [–] 8 points 11 months ago (2 children)

    Meanwhile, OP posted an article at the same time saying that amyloid proteins don't actually seem to be related to Alzheimer's: https://www.sciencedaily.com/releases/2025/11/251111005944.htm

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  • [–] 27 points 11 months ago

    That article reports that a drug targeted at clearing amyloid proteins didn’t suffice to restore the brain’s waste-clearing functionality; this article reports that a drug targeted at repairing the blood-brain barrier does restore waste-clearing functionality (including amyloid proteins). So they’re not completely contradictory.

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    • [–] 22 points 11 months ago (3 children)

    If this goes to human trials and works and then gets approved for every patient I can only imagine the hundreds of thousands of debt this will put people and their families in. It's awesome news, but the reality of it sucks

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    • [–] 8 points 11 months ago

    So, wait, we figured out how to give mice alzheimers and then cure it? 🤔

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    [–] 5 points 11 months ago

    I can't wait to share this news with my friend Charlie. Should I bring flowers?

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    [–] 3 points 11 months ago

    There's hope for me yet.

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    [–] 2 points 11 months ago* (last edited 11 months ago) (2 children)

    Mice lie. Monkeys exaggerate. Ferrets are weasels.

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  • [–] 5 points 11 months ago (1 child)

    Not nice Lie Mice lie.

    I normally don't bother with typos, but this one changes meaning significantly, for those not in the know it's a saying in biological / biomedical science about the relevance of animal testing results to humans, although I'm unfamiliar with the ferrets part, but it's cool.

    Mice lie and Monkeys exaggerate. - On the use of non-human primates in HIV research, Stephen B Weiner PhD.

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