WinApps has a nix flake. Also I don't have photoshop so I can't comment on that. However a cracked version of fl studio ran pretty well on my pc (nixos) 
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Sorry for being slightly off-topic, but I desperately wish there was a way to run the Affinity Suite reliably on Linux. I will never touch another Adobe product again and this is the only remaining pain point for me on Linux.
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Photoshop works fine for me in wine, no VM necessary, and performance is near native.
I struggled with WinApps as well. wasn't ever able to get gpu passthrough working either, and trying to do so really destabilized my computer. I pretty much gave up. That's not to say that WinApps doesn't work. It does, it's just not near native for me. There's definitely slowness, at least with Lightroom, I haven't tested with PS yet, though I have installed it.
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