There's some info here but not all the details: https://en.wikipedia.org/wiki/Woman_yelling_at_a_cat

Basically the woman in the meme was in a season of Real Housewives. She was yelling at someone who was gossiping about her husband being a violent abusive prick. The woman was trying to hide his abuse because she was scared her husband might kill her or their kids if the abuse became public. So she's basically in full flight or fight mode and terrified for her life in the meme picture because this other asshole is outing the abuse in front of everyone.

Her POS husband ended up committing suicide so at least she's safe now though. But it hit me pretty hard to find all of this out because I went through a similar situation with my mom when I was a kid.

https://knowyourmeme.com/sensitive/memes/woman-yelling-at-a-cat