I do like the few times I have seen games with two different difficulty settings and I tend to use those more. Games where they have difficulty for the action, and a separate difficulty for the puzzles.

Depending on the game, I'll crank the puzzles up to the hardest or lowest. The newer Resident Evils? Harder, pls. Onimusha back in the day where every puzzle was just a slider? Easiest. I'd skip them entirely if I could.