If manufacturing collapses in the US, it will take decades to dig out of that hole. It could be something small like the lack of a plasticizer addtive. For the want of a nail and all that.
I'm actually more concerned with this middle-case. Consider fire-retardant additives for injection-molded plastics becoming unavailable or too expensive to get. That's one of those things that requires someone to either ignore the law, or maybe politicians move the goalposts in order to save face; you wouldn't notice in the end product right away. Meanwhile, standards on consumer goods drop by just that much, and things are a little less safe. Only that times how ever many other little corner-cases like this fall by the wayside, for products in every industry (e.g. food).