I'm personally very happy with my proxmox based server(s). I'm using community scripts for many of the setups of actual services. Over all, it's low maintenance and if I'm having issues it isn't with the host system. Not once did a system update cause a failed boot after.
That being said, NASty sounds rather promising. I doubt I'll switch over, but it might at least make for a fun experiment. And being nix based is rather nice for reproducibility.