Science of information are about how knowledge, information and data is structured and stored. It is quite close to informatics but informatics has a greater focus on computing science which are the leading technology for doing just that today. Yet, they are many technology that was and are still in use to deal with information, wether it is about historic information saved in a pre-computer area or today in many places and for many reason.
It is a very deep subject, very academical and many way to practice it the most visible way to practice it is thought a computer but museum, archive, library, fond, place were electricity is not available for security or fourniture reasons are also looking for that kind of worker.