I still have some floppies in working order, even.
But no, I don't play them regularly. It's just easier to make a backup that doesn't need a disk in the drive. Even most of my retro PCs these days run out of a large-ish hard drive replacement, so keeping games outside their unreliable original media and the original media elsewhere is a better alternative.
It's a bit different on consoles where carts are harder to duplicate and ingest, as well as being more reliable and loading faster. Floppies and optical media, particularly when you can access the files, less so.