It’ll definitely be a difficult undertaking, but I plan on really trying to have a 5.25” bay when I build another PC.

That probably won’t be for a couple more years, though. I’m on a Ryzen 5 2600 and RX 580, and I really don’t do that much intense gaming; a GPU upgrade is tempting so I can actually use ROCm for some casual Blender Cycles renders, though. I hope that the already dismal supply of those 5.25 cases doesn’t dwindle even more.