You'd need to motivate rich people to go along with the balkanization, and you'd have to do it before they could be arrested for "corruption" or disappeared..

Also, to get this movement going you'd have a counter to the massive spy network that gives the feds to target and drag people out of their homes before they can cause trouble...

I think you're more likely to see rural areas secede, because those guys are Pro-Trump (decreasignly), but also very anti-federal in their bones. Most liberal coasters, driving the economy, think a USG is pretty swell.