Sara separating from Satou and his party? (When she goes to help with holy husk titan)
cover
Yes, but it does look like Sara has a dragon tail. And her expression looks to me more disturbed than just sad about the parting. The party is going and Satou is also leaving which would be after the Giant Husk left the capital. Then there are the chains, but the only chains I can think of were the ones chaining the husk's soul in the "astral plane" (for a lack of a better word) and not in the real world.
I could see the cover as a collage of separate things happening, but I don't see why they would make it look like they abandoned Sara.