I never understood the whole "bacteria can't develop resistance to soap" argument. All multi-cellular life that currently exists and that can handle soap came from single-celled life that at some point developed the ability to survive contact with soap. And while soap might have been an extreme pressure, even extreme pressures can lead to adaptations. Like there are trees that not only are fine with forest fires but even depend on them to thrive, so even fire isn't too big of a pressure for life to adapt to.

We are a species that consumes alcohol for fun. Hell, we consume hot peppers, a fruit specifically evolved to discourage mammals from eating it by causing extreme discomfort, also for fun. Life, ah, finds a way.