With invest, I take it you may mean that thing where you spend and hope for a return. But these USA fixtures can be instant wins. The Springboks vs All Blacks game in Baltimore will be in front of more than 62,300, making a heap more more money for both the Springboks and All Blacks than any of the ones played in South Africa. It will be the most-attended single rugby match in North American history - not only making money but also showcasing the game.
Nations Cup games would be great for this idea as well - not only in America but also in other places you mentioned such as Madrid