No I mean there's for sure localized slang, but "ice" and "crystal" don't mean "mushrooms" anywhere, they always mean meth. Sure your state may call them "mushies" or "shrooms" or your friend group can have a specific codeword like "cheetos" (or context dependent but non established code words, yesterday one of my plugs asked if I need any "crayons" which is not a thing at all but he only sells one thing so I know what it is), but the aforementioned slang terms always means mushrooms. Some areas know a "slice" means an eighth, some don't, the Bay Area might still call mid "bammer," there's definitely local slang, and I'll even give you that some (like dro) loses it's meaning (hydroponic) and just starts to mean any loud, but you understood literally every term I just said to mean what I intended because nowhere on earth does "dro" mean "methylphenidate."