I'm personally running Artix with runit and things are fine so far, but as ChrisG pointed out, dinit is basically a drop-in replacement for systemd syntax-wise.

Although if you're on Artix, you'll need to enable Arch's [extra] and [multilib] repos or you'll run into dependency issues on some apps due to some packages not being available in the main Artix repos. I learned this when trying to install steam-native-runtime, there were some Python deps which weren't available in the main Artix repos, but that were available in the Arch repos, if I'm remembering right.

Also, I recommend enabling the unofficial [liquorix] repo in order to get a newer kernel with more frequent updates than what Artix provides in their repos, eg. the default and zen kernels in the Artix repos lag a bit behind the lqx kernel from the [liquorix] repo, and I still recommend enabling [chaotic-aur] as a convenience repo on any Arch distro.

I also switched to MATE from KDE out of concern that KDE could end up following GNOME's path after SDDM is deprecated, plus I just wanted a lighter and different desktop, that and MATE's default two-panel layout is completely usable from stock although you might wanna set the panels to auto-hide to maximize screen space.