It’s all subjective and based on your personal level of interest. From a technical standpoint the time needed is based on how fast your computer can compile everything, how fast you read and understand the instructions, and how much effort you want to put into it.

So yeah, a weekend could be reasonable.

When I last set up LFS it took a week, but I read everything. I was doing it to better understand how Linuxes work

...that was a full week, it would have taken much longer had I had other things to do