Europa Universalis IV 90% off. Alan Wake 90% off. Prince of Persia series 80% off. Devil May Cry 1-4 67% off. Various Hitman games 90% off - the original is going for 79 cents. I could go on but I dunno what you'd be into. They have more recent games too, like Baldur's Gate 3 20% off.

Anyway, mostly they're the same discounts as on Steam at the moment so I dunno if it counts as "of note". I just mention it because if you buy with GOG you get the game DRM-free, plus some people prefer to spend their money with the EU (as opposed to the USA) these days for obvious reasons.