I have nginx set up for limited stuff, most of my selfhosted services I kept behind tailscale.
The only big con I found against it, it's hard to switch between the self-hosted and "normal" vaults. I should test if I can have another copy (eg appimage) with separate settings for that.
I am heavily using the local-only mode but I've also recommended it to some normie friends, so sharing vaults in different modes becomes a hassle
Edit: tldr, I'm using the "local only" mode but since I have tailscale, everywhere is LAN ;)