Thanks for the tip.
I googled and came across a small guide how to actually do it (for everyone else that's stumbling across this post):
Start button>%appdata%>Arrowhead>Helldivers2
You want to delete the "Helldivers2" folder, and re launch the game.
This will reset all settings, but fix hard locks.
Worked for me and 6 others
It is likely a shader issue, or something of the like.
Source: https://www.reddit.com/r/Helldivers/comments/1oevtgc/how_to_permamently_fix_hard_locking/