My problem is usually width. Most vehicles aren't built for anyone physically wider than average (while yes, i am also overweight, id still have this problem no matter what). Some office chairs give me hip pain, and most armrests can't be adjusted out far enough to not be digging into my ribs.

There's also just nowhere for my left leg to comfortably go in an automatic, at least with a manual i had the clutch to keep that leg moving.