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Thalidomide was first developed as a tranquilizer by Swiss pharmaceutical company Ciba in 1953. In 1954, Ciba abandoned the product, and it was acquired by German pharmaceutical company Chemie Grünenthal.[4] The company had been established by Hermann Wirtz Sr, a Nazi Party member, after World War II as a subsidiary of the family's Mäurer & Wirtz company. The company's initial aim was to develop antibiotics for which there was an urgent market need.
https://en.wikipedia.org/wiki/Thalidomide_scandal
I start to think that those Nazi people made bad thing happening on earth
The problem with this logic is that it extends to literally every business that existed in Germany during or immediately after WWII. The guy who exposed thalidomide as a teratogen and all but stopped its use worldwide had also been a Nazi. In reality, the pharmaceutical industry in all countries in the 40s and 50s had few to no guardrails and they caused a lot of inadvertent damage
I used to manipulate those at an old job. Even if they were packaged, I had to wear a mask and gloves every single time. They also made us read multiple articles with photos of terrible birth defects. They weren't fucking around.
What are the tins on the picture? Considering the capsules can't be too large for swallowing whole, the tins must be tiny. Yet contain 25 tablets? I'm confused.
It looks like the tins aren't related to the doses in cardboard, they're other brand names/formulations of thalidomide that are all different dosages. I see distaval 25mg and 100mg there. They also look old and may be antiques vs the new way it's distributed
Three women were sitting down and knitting onesies talking about being pregnant for the first time. The first woman reaches down and takes a pill out of her purse and pops it in her mouth. The other women just stare at her. The first woman says "It's a calcium supplement, I want my baby to have strong bones." then she goes back to knitting.
The second woman reaches into her purse and grabs a pill and then pops that into her mouth. The other two women stop and stare at her. The second woman announces "It's vitamin e, I want my baby to have strong hair and good skin" The second woman then resumes her knitting.
The third woman then reaches into her purse and takes a pill and pops that one into her mouth. The other two women stop and stare at her. She says "it's thalidomide, I don't know how to knit sleeves."
One of my childhood (maybe around 9?) memories is me sitting in a bus with my mom, and me noticing a woman a couple seats over. who basically just had hands attached to her shoulders. Almost no arms whatsoever
My mom noticed me staring and nudged me. Later she tried to explain why the woman looked like that
This drug is such a tragic medical story
This is for Americans. Let that sink in. WE need these warnings...and a lot ( and I mean A LOT) won't see these warnings.
Are you trying to say people in many countries wont see these warnings because of weak regulations for the pharmaceutical industry? I dont get what you mean when you say "WE (Americans) need these warnings," because that sounds like youre saying Americans are so stupid they need the warnings when I would say that everyone should be warned about thalidomide side effects.
actually, the FDA refused to approve this drug, which is why we don't have a generation of people with terminal limb deformities from it.
Reminds me.. back in the 90s I had two Miatas, one imported from Canada and one from the US. In the operating manuals, one difference that stood out in the US manual was the inclusion of a warning to not stand while driving.
Those poor Canadian Miata owners didn't stand a chance, did they.
Huh.. I don’t understand your point. So you think we should just know that this medicine is dangerous for pregnant women?
No we don’t, because it wasn’t approved in the US until the late 90s and only for treating VERY specific cancers.
It was pushed out in West Germany in the 50s specifically as a morning sickness med while pregnant, which is why these warnings are on there.
Eh, kinda a stretch to make this about Americans.
In the original thalidomide problem it was the same 'paranoia' that kept it entirely off the market in the US.
Beyond that, I'm not sure I get the reasoning behind "Americans are so dumb that they put safety and usage instructions on cancer medication, with emphasis on the most severe warnings!”
Why wouldn't you want to label dangerous things that are actually, uniquely hazardous?
I believe, in general, it's a lot harder to hold a company liable for your own stupidity in Europe.
It's still used for treating severe nausea in pregnant women, even. In life and death cases.
Pregnancy. Such fun.
You have a source for that? Nausea is just a symptom and can't really be life and death by itself.
Thalidomide is still mainly used for the treatment of multiple myeloma and leprosy.
Also a fun fact is that the US was basically unaffected by the thalidomide crisis because a pharmacologist employed by the FDA refused to approve the medication on the basis that it lacked sufficient clinical trials. Frances Oldham Kelsey resisted pressure from the company that was trying to sell the medicine in the US and only 17 people were affected in the US compared to the 20000 figure cited for global cases. JFK awarded her with a presidential award for her service.
No it isn't. There's plenty of safe anti-nausea medication on the market why would they use something like this that would cause birth defects?
Also as far as I'm aware preventing nausea isn't even one of its effects. When are you getting this information from?
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