ClickFix attacks often prey on the fact that people don't understand what key combinations do. The examples I've dealt with professionally (read: my company's users ran into them), have directed the user to press the following keys in order:
+R
+V
Some folks may recognize the +V as paste, but many don't and only think of + as paste. And it's mostly tech-savvy people who would recognize +R as opening the run box. Since the code gets pre-loaded in the clipboard with JavaScript, the user never sees the code on the webpage and may not realize that their clipboard is loaded with the malicious code. Again, for tech-savvy users, this should be obvious. For everyone else, it's just another annoying CAPTCHA they have to deal with.