Station eleven had a really unique format. You could say there were multiple main characters from different timelines but I would almost argue there was not a "main" character. All of them were super fascinating in their own right and the transitions between them, and their timelines, was incredibly smooth. I didn't find it confusing at all and I normally do with books formatted like this.
It's a post pandemic dystopia that focuses on the role of art in helping people find purpose if you want the shortest possible synopsis.