I’m in a blue state, so not very. But I work in an interesting environment where people hold a lot of conspiratorial and junk-science views (recently there was a rumor about an upcoming seven-second loss of gravity.) I navigate it with shutting down any sense that I would ever humor it. I don’t maintain any sort of connection beyond general courtesy otherwise. Worst case was “we have to agree on reality to discuss it” and that was that.