I would actually love to see an adaptation of Asteroids. You have a lot of options.
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A ship/station’s automated defense system fails, so humans have to use manual targeting to fend off a rock storm as the structure sustains more and more damage.
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Mining operation goes bad, with or without aliens/microbes.
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Rockbusters clearing a shipping lane encounter aliens, but nobody believes the first guy to see them because they just did a quick drive-by.
…and many more!