Of course. I think there are many things that we haven't detected because we lack the instruments or even the concept they exist

Humans are constantly discovering life on Earth in places it was thought impossible, like deep underground or in very hot water around volcanic vents.

Certain cancers (HPV, EBV, HBV) have been discovered to be caused by viruses, not just randomly out of control cell replication.

IMO even astronomers suffer from short-sightedness. They tend to classify things in terms of our own little solar system when actually with billions of stars and trillions of planets there are likely very many astronomical objects and phenomenon that we have never observed or thought of.