I've heard self-hosters say USB isn't great for server / NAD drives long term but I don't know where they get that. It actually sounds pretty rad to have a small server plugged into a powerful dedicated enclosure! Especially with those Thunderbolt speeds.
But wow that IS stupidly complicated. I have all those different USB ports on my motherboard IO and I get the nagging feeling I'm not taking advantage of them but also...whatever, don't care, they do the simple jobs. Lol