Depending on how you define "self-hosting", I may qualify at that.

I've hosted my email on a remote VPS myself. I have not hosted the machine in my apartment.

I used postfix + dovecot + mysql stack, I have to admit it was the hardest thing I've ever configured and I've hosted a lot of services in my life.

In the end I ended up switching to the free service that came with the domain became no matter what I did and how compliant I was to dkim and SMARC and tkip (I'm probably butchering the name here, it's been a long time) outlook accounts kept sending my emails to spam, everything else worked fine, even gmail, but DAMN Microsoft and how much I hate that company managed to fuck over me one final time even after years after I switch to Linux. I tried everything even the form to remove my email from spam.

Tl;Dr hosted email on a vps but couldn't get past outlook spam filters