Thank you very much Botzo. I finally wrapped my head around this. Flatpak first, then spin up a container of an operating system for one lousy app and only use ostree as last resort. I had it backwards after decades of doing it the other way lol.
Take a look at the difference in resource usage would you:
Skanlite Rpm installed size - 3mb
Skanlite Flatpak installed size - 16mb (plus Flatpak run time files etc)
Not even gonna guess how much a container of Fedora 43 in Distrobox just for one 3mb application is going to consume lol.
For me, the voracious storage consumption is something to stop and consider ...