I hate this sorta thought process. He was sick. He was a serial killer. He had serious mental issues. He was making a fucking skin suit. Nobody is assuming this was or wasn’t because of the trans-sexual implications. It’s no different than the belly aching about the albino bad guys in The Matrix. It was a character not social commentary about all trans people for fucks sake.
Edit: There is nothing wrong with being trans. But if every bad guy in every movie or story is a straight white guy, the stories are gonna get kinda boring real quick.