Definitely not impossible! Speaking of Docker, there is even a sort of "compatibility layer" in the (oci-service-type) in Guix now, which seems pretty similar to me to what Docker compose does w/ the .yaml files but done in Scheme. I've got most of my Docker containers sorted out this way as part of the broader system config, which is just awesome for things that don't have dedicated services in Guix proper. Once it's not a complete dumpster fire and I feel comfortable showing it you can check git.bluechateau.org and it should all be there at some point! I only really barely know what I'm doing, but I love it.