Yup. Same with any other as well. If you don't want to use Steam, I think a lot of people find Lutris and Heroic simple.and functional for all levels of user, and they also include the ability to run Steam Runtimes and Proton versions pretty simply too.

All of these launchers run Wine under the hood, and are a good abstraction on top of that entire stack. Just makes it super simple to manage.

Heroic also has an option to move games to a different directory so you can move them between drives easily after they're already installed.