Start by figuring out the primary purpose of each space. What functions does it need to enable? Start prioritizing the layout and design options that support those functions... make sure things that are used together are near each other, make sure that if it's oriented around a task tv watching or music listening or reading that the glare / angles / room treatments are are appropriate, then work on aesthetics from there. And experiment a lot. Don't solidify until youre really happy.
Architects and interior designers constantly prototype and try different layouts and configurations before settling on a design. And prototyping means easy low fidelity options that can be changed and discarded. Literally build shelves and stuff out of cardboard boxes and milk crates until you figure out what you want where and how to organize it, then invest in building slightly more permanent ones, then even more permanent ones.