So reading the title I came to say yes with a caveat but you included the caveat. The thing is self interest is ultimately about happiness but humans don't always understand what brings it. Drug use is sorta the basest level. Chasing literal physcial sensation of pleasure. Sex addiction would be next which is really just chasing drugs that our body naturally makes. Same with danger addiction and such. Then you get to like food addiction. Next is money addicition which is sorta looking at it as a gateway to everything. Recognizing how important others are on different levels means a lot. Its a bit like the hierarchy of needs. You can maybe get physiological on ones own but after that any increase in actual happiness involves having to improve your environment and society and ultimately the earth. So I guess Im saying yes but people can pervert it for not seeing the forest for the trees.