I definitely did feel a little out of place around men, and many of my friends were women (even before my egg cracked). Uneasy is probably the wrong word, more just like an outsider.

I definitely wouldn't make the claim "men are not that well socialized" (although that may well be true - but I couldn't speak to that purely from my own experience)

While not a trans man, I have a great many friends that are - and all of them have really struggled with the social isolation men face. "It shouldn't be like this" no shit dude, but this is unfortunately what you signed up for and it's gonna be a fuck of a lot of work to fix it, welcome to the team.

Geographically it can be better because queer folks tend to stick together, but outside of queer spaces... yeah, it's rough out there.