Frankly, with my screwed up brain, I document everything. I can turn around twice in my lab and my brain will flat line. When I first started, I would always tell myself that I'd remember stuff. Not anymore.
I created a script for Linux that automatically backs up to a NAS drive, once every two weeks, as a complete image, and I keep 5 on deck. Testing usually happens once every 3 months or so. I also have Duplicati backups that are stored offsite on my VPS.