The calories hit basically the same. The carbs might be closer to sugar and combined with the missing fiber you'll get a big insulin spike. Gotta watch out for those to not build resistance.

But there is this obsession with the "chemicals" like the Red dye 40 scare recently. Those are like 0.5% of the problem, but distract from the real problem of too many calories.

The point at which you should care about Red40 is when you're a professional athlete or bodybuilder on contest prep. No normal human has health issues from these "chemicals" (allergies notwithstanding) anywhere comparable to the issues of too many calories.

Edit: As a German I do agree that American "Bread" should be classified and sold as dishwashing sponges.