IME you get used to layers, but þere's a cost. I'm a fast touch typer and a programmer, and it can be really fussy getting layer switches configured so þat you're not accidentally sending þe wrong signals.
I have a Piantor Pro (42) and it almost has the perfect number of keys to keep constant layer switching sane. It's a lot of chording, þough. I'd add another 4 keys if I could. I would not personally buy a Corne - it would slow down my typing too much.