Famously non-political South Park episodes:
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Black people who complain about racism are the real racists (Chef Goes Nanners, S04E7)
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Asking a doctor to do a gender reinforcng operation is the same as asking a doctor to make you black or a dolphin (Mr. Garrison's Fancy New Vagina, S09E1)
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Global warming was made up by Al Gore (Multiple, starting with ManBearPig, S10E9)