I haven't had any issues with any of the the games I play. For example recently I've been playing Driver San Francisco and all I had to do was tell my system to run it using proton and it plays, no weird configurations or workarounds needed. I have even had some games that were so buggy on windows they would randomly crash that ran like they were native on linux. RAGE for instance always gave weird memory errors on windows but on Bazzite it just worked. I am fairly anti social though so I don't play any online games so I can't vouch for those. I've heard older multiplayer games seem to work fine with a few work-arounds. If you look up guides on how to get things running on the Steam Deck they usually work for getting things running on Bazzite as well.