You should know nvidia is the worst and it is definitely an nvidia problem. Nothing else (even DNS) is, such a pain on linux. Nvidia routinely ships broken software on their stable branch even for their top of the line consumer cards.

I have two 4k monitors and run many flavors of Linux as daily drivers. Plus I have a 4090. It's not a super common setup but for a company as huge as nvidia they should be testing dual monitor setups and it is clear they do not. I have stopped updating my nvidia drivers after the 3rd time I lost basic functionality after a driver update.