So here's the thing with massive individual drives. Assuming you're buying multiples for redundancy (say 4 for a 3+parity stripe), you'll probably come out ahead cost wise over a similar total capacity with "normal" sized 12TB drives.

But if one of those drives fail, assuming your consumption is around 60-75%, the rebuild time is going to be massive.

For comparison, I just upgraded from 6TB drives in my Synology 5-bay. It was pushing 90% utilization. Doing a drive by drive swap, waiting for the parity to rebuild as I replaced each one with a 10TB drive - it was the better part of 5 days.

If you are thinking of using it as a standalone drive (no redundancy), your back up plans better be solid, testable, and off to a different system (no relying on time shift to the same drive).