It's top down Noita, or BoI+Noita. I have 1k hours and am still discovering new effects and combinations every run, it's nuts!

Pro tip: I wanted to milk it for all its got, so after reaching endgame content, I started a new toon and limited myself to 2 wands and no upgrades to life mana, starting stuff like keys or coins. Just "tentacle girl" updates and it's been really good. I die because of mistakes, not because of balance. Otherwise, you'll get a bit too strong and steamroll every enemy and boss at some point (100 hours in or so).