What I do most of the time is have the /home directory on a different partition. If you really do need to reinstall, it is just a matter of selecting the existing home partition when reinstalling it (do not forget to uncheck the "format partition" checkbox 😅).

Reinstalls or running other distro's is a piece of cake this way.

My experience with amd / radeon has not been that great over the years. The open source amdgpu driver is basic at best. If you have a modern intel gfx chipset that is way easier...