The analogy makes a lot of sense to me. Once you have an "easy button", it's hard to not use it. It's sort of like when you're at work and see the "quick workaround" effectively become the standard process.
I remember burning out on games because the cheats made them really fun in the short term, but afterward playing normally felt like agony.
Nah, the knowledge that I could be locked out of unique items is what caused anxiety, not what I was actually locked out off (though I do think it's a really good item for a ring). I played act 1 as a blundering fool, at the end of act 1 I checked an item list to see what I missed, so I could backtrack for what I could use. And then I destroyed my fun in act 2 by checking guides before starting an area.